2,4,6-trisubstituted pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer

Details for Australian Patent Application No. 2003295776 (hide)

Owner Novartis Vaccines and Diagnostics, Inc.

Inventors Renhowe, Paul A.; Nuss, John M.; Pecchi, Sabina

Agent FB Rice

Pub. Number AU-B-2003295776

PCT Number PCT/US2003/0372

PCT Pub. Number WO2004/048365

Priority 60/438,568 07.01.03 US; 60/523,081 19.11.03 US; 60/428,473 21.11.02 US

Filing date 21 November 2003

Wipo publication date 18 June 2004

Acceptance publication date 12 May 2011

International Classifications

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

A61P 35/00 (2006.01) Antineoplastic agents

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/46 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 401/14 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/04 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 403/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 405/14 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

C07D 413/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms

C07D 417/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

C07D 417/14 (2006.01) Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group

Event Publications

22 April 2004 Complete Application Filed

  Priority application(s): 60/438,568 07.01.03 US; 60/523,081 19.11.03 US; 60/428,473 21.11.02 US

22 July 2004 Application Open to Public Inspection

  Published as AU-B-2003295776

30 October 2008 Alteration of Name

  The name of the applicant has been altered to Novartis Vaccines and Diagnostics, Inc. 2004

12 May 2011 Application Accepted

  Published as AU-B-2003295776

8 September 2011 Standard Patent Sealed

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