Cyclohexyl sulphone derivatives as gamma-secretase inhibitors

Details for Australian Patent Application No. 2003267614 (hide)

Owner Merck Sharp & Dohme Limited

Inventors Williams, Susannah; Teall, Martin Richard; Churcher, Ian; Kerrad, Sonia; Shaw, Duncan Edward; Oakley, Paul Joseph; Harrison, Timothy

Agent Spruson & Ferguson

Pub. Number AU-B-2003267614

PCT Number PCT/GB03/04102

PCT Pub. Number WO2004/031137

Priority 0223039.9 04.10.02 GB

Filing date 25 September 2003

Wipo publication date 23 April 2004

Acceptance publication date 18 February 2010

International Classifications

C07C 317/14 (2006.01) Sulfones

C07C 317/18 (2006.01) Sulfones

C07C 317/20 (2006.01) Sulfones

C07C 317/22 (2006.01) Sulfones

C07C 317/24 (2006.01) Sulfones

C07C 317/44 (2006.01) Sulfones

C07C 331/04 (2006.01) Derivatives of thiocyanic acid or of isothiocyanic acid

C07D 205/04 (2006.01) Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom

C07D 207/48 (2006.01) Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

C07D 211/96 (2006.01) Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings

C07D 213/70 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/71 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 213/89 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 233/84 (2006.01) Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings

C07D 239/38 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 249/08 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 249/12 (2006.01) Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms

C07D 257/04 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 277/36 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 285/125 (2006.01) Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups

C07D 295/092 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 295/26 (2006.01) Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

C07D 307/38 Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom

Event Publications

8 January 2004 Complete Application Filed

  Priority application(s): 0223039.9 04.10.02 GB

27 May 2004 Application Open to Public Inspection

  Published as AU-B-2003267614

18 February 2010 Application Accepted

  Published as AU-B-2003267614

17 June 2010 Standard Patent Sealed

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