Owner The Brigham and Women's Hospital, Inc.

Inventors Palmer, Glyn; Evans, Christopher; Pascher, Arnulf; Ghivizzani, Steven

Agent Davies Collison Cave

Pub. Number AU-B-2003247492

PCT Number PCT/US03/17753

PCT Pub. Number WO2003/104402

Priority 60/386,870 06.06.02 US

Filing date 6 June 2003

Wipo publication date 22 December 2003

Acceptance publication date 14 May 2009

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 9/50 (2006.01) Medicinal preparations characterised by special physical form - Microcapsules

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 47/46 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Ingredients of undetermined constitution or reaction products thereof

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 17/02 (2006.01) Drugs for dermatological disorders

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells