Owner SmithKline Beecham Corporation

Inventors Lee, Jinhwa; Aubart, Kelly M.; Christensen, Siegfried B. IV; Silva, Domingos J.; Karpinski, Joseph M.; Benowitz, Andrew B.

Agent Davies Collison Cave

Pub. Number AU-B-2003247445

PCT Number PCT/US03/17054

PCT Pub. Number WO2003/101442

Priority 60/384,457 31.05.02 US

Filing date 30 May 2003

Wipo publication date 19 December 2003

Acceptance publication date 26 February 2009

C07C 243/34 (2006.01) Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes

A61K 31/16 (2006.01) - Amides, e.g. hydroxamic acids

A61K 31/18 (2006.01) - Sulfonamides

A61K 31/44 (2006.01) - Non-condensed pyridines

A61K 31/495 (2006.01) - having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

A61K 31/50 (2006.01) - Pyridazines

A61K 31/505 (2006.01) - Pyrimidines

C07C 243/22 (2006.01) Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes

C07C 255/66 (2006.01) Carboxylic acid nitriles

C07C 259/06 (2006.01) Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups

C07C 311/16 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07C 311/39 (2006.01) Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups

C07D 213/77 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 215/12 (2006.01) Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems

C07D 237/20 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 237/22 (2006.01) Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/48 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/70 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/95 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/44 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 251/18 (2006.01) Heterocyclic compounds containing 1,3,5-triazine rings

C07D 251/22 (2006.01) Heterocyclic compounds containing 1,3,5-triazine rings