Owner Janssen Pharmaceutica N.V.

Inventors Van Reempts, Jozef Leo Henri; Gomez-Sanchez, Antonio; Leenaerts, Joseph Elisabeth; Van Rossem, Koenraad Arthur; Tegtmeier, Frank; Martinez-Jimenez, Pedro; FernandezGadea, Francisco Javier; Janssens, Frans Eduard; Alcazar-Vaca, Manuel Jesus; Bartolome-Nebreda, Jose Manuel

Agent Shelston IP

Pub. Number AU-B-2002356715

PCT Number PCT/EP02/13180

PCT Pub. Number WO2003/044023

Priority 01204574.6 23.11.01 EP

Filing date 22 November 2002

Wipo publication date 10 June 2003

Acceptance publication date 15 May 2008

C07D 487/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

A61K 31/513 (2006.01) - having oxo groups directly attached to the heterocyclic ring, e.g. cytosine

A61K 31/517 (2006.01) - ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

A61K 31/519 (2006.01) - ortho- or peri-condensed with heterocyclic rings

A61K 31/55 (2006.01) - having seven-membered rings, e.g. azelastine, pentylenetetrazole

A61P 1/04 (2006.01) Drugs for disorders of the alimentary tract or the digestive system

A61P 9/10 (2006.01) Drugs for disorders of the cardiovascular system

A61P 29/00 (2006.01) Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents

A61P 37/02 (2006.01) Drugs for immunological or allergic disorders

A61P 37/06 (2006.01) Drugs for immunological or allergic disorders

A61P 37/08 (2006.01) Drugs for immunological or allergic disorders

C07D 471/00 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 471/04 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups

C07D 487/00 (2006.01) Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups

C07D 519/00 (2006.01) Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or