Aryl and Heteroaryl Urea CHK1 Inhibitors for Use as Radiosensitizers and Chemosensitizers

Details for Australian Patent Application No. 2002258451 (hide)

Owner ICOS Corporation

Inventors Gaudino, John Joseph; Keegan, Kathleen, S.; Cowen, Scott Douglas; Kesicki, Edward A.; Burgess, Laurence Edward; Cook, Adam Wade

Agent Wrays

Pub. Number AU-B-2002258451

PCT Pub. Number WO2002/070494

Priority 60/273,124 02.03.01 US

Filing date 1 March 2002

Wipo publication date 19 September 2002

Acceptance publication date 31 August 2006

International Classifications

C07D 241/20 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

A61K 31/4965 (2006.01) - Non-condensed pyrazines

A61K 31/498 (2006.01) - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine

A61P 35/00 (2006.01) Antineoplastic agents

C07D 213/75 (2006.01) Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members

C07D 231/40 (2006.01) Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings

C07D 239/42 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 239/46 (2006.01) Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings

C07D 241/54 (2006.01) Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings

C07D 251/22 (2006.01) Heterocyclic compounds containing 1,3,5-triazine rings

C07D 253/06 (2006.01) Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 257/06 (2006.01) Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms

C07D 277/48 (2006.01) Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings

C07D 401/12 (2006.01) Heterocyclic compounds containing two or more hetero rings

C07D 403/12 (2006.01) Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group

C07D 405/12 (2006.01) Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom

Event Publications

13 March 2003 Application Open to Public Inspection

  Published as AU-B-2002258451

26 August 2004 Amendment Made

  The nature of the amendment is: Amend the invention title to read Aryl and Heteroaryl Urea CHK1 Inhibitors for Use as Radiosensitizers and Chemosensitizers

31 August 2006 Application Accepted

  Published as AU-B-2002258451

4 January 2007 Standard Patent Sealed

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