Modified anti-EGFR antibodies with reduced immunogenicity

Details for Australian Patent Application No. 2002249224 (hide)

Owner Merck Patent GmbH

Inventors Williams, Stephen; Jones, Tim; Carr, Francis J.; Carter, Graham; Hamilton, Anita

Agent Davies Collison Cave

Pub. Number AU-B-2002249224

PCT Pub. Number WO2002/066058

Priority 01103954.2 19.02.01 EP

Filing date 18 February 2002

Wipo publication date 4 September 2002

Acceptance publication date 3 May 2007

International Classifications

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

A61K 9/70 (2006.01) Medicinal preparations characterised by special physical form - Web, sheet or filament bases

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 45/00 (2006.01) Medicinal preparations containing active ingredients not provided for in groups

A61K 47/02 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Inorganic compounds

A61K 47/12 (2006.01) Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives - Carboxylic acids

A61P 35/00 (2006.01) Antineoplastic agents

A61P 43/00 (2006.01) Drugs for specific purposes, not provided for in groups

C07K 14/54 (2006.01) Peptides having more than 20 amino acids

C07K 16/18 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - against material from animals or humans

C07K 16/28 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/30 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C07K 16/46 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies - Hybrid immunoglobulins

C07K 19/00 (2006.01) Hybrid peptides

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

G06F 19/00 (2006.01) Digital computing or data processing equipment or methods, specially adapted for specific applications

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 38/11 (2006.01) Medicinal preparations containing peptides

Event Publications

27 February 2003 Application Open to Public Inspection

  Published as AU-B-2002249224

3 May 2007 Application Accepted

  Published as AU-B-2002249224

30 August 2007 Standard Patent Sealed

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