Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins

Details for Australian Patent Application No. 2002226390 (hide)

Owner 4-Antibody AG

Inventors Grawunder, Ulf; Melchers, Georg Friedrich

Agent Phillips Ormonde Fitzpatrick

Pub. Number AU-B-2002226390

PCT Pub. Number WO2003/068819

Filing date 22 December 2001

Wipo publication date 4 September 2003

Acceptance publication date 15 November 2007

International Classifications

C12N 5/10 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

A61K 35/14 (2006.01) Medicinal preparations containing material or reaction products thereof with undetermined constitution - Blood

A61K 38/00 (2006.01) Medicinal preparations containing peptides

A61K 39/00 (2006.01) Medicinal preparations containing antigens or antibodies

A61K 39/395 (2006.01) Medicinal preparations containing antigens or antibodies - Antibodies

A61K 48/00 (2006.01) Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases

A61P 37/04 (2006.01) Drugs for immunological or allergic disorders

C07K 16/00 (2006.01) Immunoglobulins, e.g. monoclonal or polyclonal antibodies

C12N 5/06 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines -

C12N 5/20 (2006.01) Undifferentiated human, animal or plant cells, e.g. cell lines - one of the fusion partners being a B lymphocyte

C12N 15/09 (2006.01) Mutation or genetic engineering - Recombinant DNA-technology

C12P 21/02 (2006.01) Preparation of peptides or proteins - having a known sequence of two or more amino acids, e.g. glutathione

C12P 21/08 (2006.01) Preparation of peptides or proteins - Monoclonal antibodies

Event Publications

2 October 2003 Application Open to Public Inspection

  Published as AU-B-2002226390

15 November 2007 Application Accepted

  Published as AU-B-2002226390

13 March 2008 Standard Patent Sealed

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